Care from Home
Handle the entire process online without waiting rooms or in-person visits.
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Your order ships quickly within 1–2 days at no cost and arrives in plain, private packaging.
Guided Treatment
Easy weekly dosing steps and clear instructions support you through each stage.
Explore Contrave® for your weight loss goals with a free online questionnaire.
Start Free ConsultationTreatment
Supports weight management by regulating appetite and cravings. Treatment begins with a structured four-week titration plan before moving to twice-daily dosing. Each tablet contains 8 mg of naltrexone hydrochloride and 90 mg of bupropion hydrochloride.
How It Works
Contrave® is a prescription medication used to support weight management in adults with obesity or adults who are overweight and have a related health condition. It contains two ingredients, naltrexone and bupropion, that act on distinct brain regions involved in appetite, cravings, and eating behavior. Together, they help reduce hunger signals and curb urges to overeat.
Contrave® titration schedule
Contrave® uses a four-week titration plan to help your body adjust to treatment. Each tablet contains 8 mg of naltrexone hydrochloride and 90 mg of bupropion hydrochloride.
Week 1
Week 2
Week 3
Week 4
Do not take more than 2 tablets at one time or more than 4 tablets in a day.
Your first 4 weeks on Contrave® follow a structured dose increase. Once you reach the maintenance phase after week 4, take the medication twice a day.
Common side effects include:
More serious reactions are possible, such as seizures, allergic reactions, mood changes, or opioid overdose if Contrave® is taken with opioids.
Seek medical attention if you experience any concerning or lasting side effects.
Contrave® can interact with several types of medications.
Use caution with:
Always tell your healthcare provider about all medications, supplements, and over-the-counter products you take.
45.8% of those treated with Contrave® reached 5% or greater weight loss at 16 weeks. (Source).
HOW IT WORKS
A licensed clinician partnered with Treat Me Now will review your medical history and preferences to create your treatment plan. Most reviews are completed within 24 hours of finishing step 1, and the consultation process is completely free.
TreatMeNow is a safe telehealth option for starting Contrave®. Your details are kept confidential, and the online process is set up to help you begin treatment quickly and comfortably from home.
Skip the missed tablet and wait for your next scheduled dose. Do not take extra tablets to make up for a missed dose, since this increases the risk of seizures.
Contrave® is not recommended during pregnancy. Speak to your healthcare provider before starting or continuing treatment if you are pregnant or planning to become pregnant.
Start by completing a free and quick online questionnaire. After your information is reviewed, a prescription may be issued if Contrave® is appropriate for you.
Contrave® can make you more sensitive to alcohol, so even small amounts may affect you more than usual. Drinking while on Contrave® can raise the risk of seizures or allergic reactions, so avoiding alcohol during treatment is recommended.
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Still have questions?
Contrave® is a prescription medication used to support weight management in adults with a body mass index (BMI) of:
Contrave® combines naltrexone and bupropion, which affect two brain systems: one connected to appetite and another involved in reward-driven eating.
Follow the weekly schedule. Contrave® is taken twice daily, with a structured titration over the first four weeks. Do not exceed 2 tablets at one time or 4 tablets per day.
Take with food. Each dose should be taken with food. Avoid high-fat meals, which may increase the risk of seizures.
Swallow tablets whole. Do not cut, crush, or chew the tablets.
Missed dose. If you miss a dose, wait until your next scheduled time. Do not take extra tablets to make up for a missed dose.
Common side effects include:
More serious reactions include:
Seek medical care if you experience any persistent side effects.
Contrave® can interact with:
Always tell your healthcare provider about every medication, supplement, and over-the-counter product you take.
Active ingredients:
Inactive ingredients:
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